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High-Density DNA and RNA microarrays - Photolithographic Synthesis, Hybridization and Preparation of Large Nucleic Acid Libraries
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In situ oligonucleotide synthesis on carbon materials: stable substrates for microarray fabrication

Margaret F Phillips1, Matthew R Lockett, Matthew J Rodesch

  • 1Department of Chemistry, University of Wisconsin - Madison, 1101 University Ave. Madison, Madison, WI 53706, USA.

Nucleic Acids Research
|December 18, 2007
PubMed
Summary

Researchers developed more stable DNA arrays using carbon-based substrates instead of traditional glass. These new arrays resist degradation in water, enabling advanced applications like high-temperature hybridization for DNA analysis.

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