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Crystallization and preliminary crystallographic analysis of the Tob-hCaf1 complex

Kinya Nishida1, Masataka Horiuchi, Nobuo N Noda

  • 1Department of Structural Biology, Graduate School of Pharmaceutical Science, Hokkaido University, N12, W6, Kita-ku, Sapporo 060-0812, Japan.

Acta Crystallographica. Section F, Structural Biology and Crystallization Communications
|December 18, 2007
PubMed

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In the late 1800s, the revelation that light extended beyond visible wavelengths led to the discovery of X-rays by Wilhelm Roentgen. Recognized as high-energy electromagnetic radiation with short wavelengths, X-rays prompted exploration into their interaction with crystals. Max von Laue proposed in 1912 that the periodic arrangement of atoms, ions, or molecules in crystals would cause them to diffract X-rays, a hypothesis confirmed through experiments with copper sulfate and zinc sulfide...
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The size of the unit cell and the arrangement of atoms in a crystal may be determined from measurements of the diffraction of X-rays by the crystal, termed X-ray crystallography.
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