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Ewing's sarcoma: imaging features.

B Peersman1, F M Vanhoenacker, S Heyman

  • 1Dept. of Radiology, University Hospital Antwerp, Belgium. benjaminpeersman@hotmail.com

JBR-BTR : Organe De La Societe Royale Belge De Radiologie (SRBR) = Orgaan Van De Koninklijke Belgische Vereniging Voor Radiologie (KBVR)
|December 19, 2007
PubMed
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Ewing sarcoma (ES) primarily affects young patients, with pelvic and femur locations being most common. Imaging reveals a large soft tissue mass, often with a spiculated periosteal reaction, aiding in diagnosis.

Area of Science:

  • Oncology
  • Radiology
  • Pediatric Oncology

Background:

  • Ewing sarcoma (ES) is a rare bone cancer predominantly affecting children and young adults.
  • Accurate imaging is crucial for diagnosis, staging, and treatment planning of ES.

Purpose of the Study:

  • To establish an imaging prototype for Ewing sarcoma (ES).
  • To correlate imaging findings with clinical and pathological data in ES patients.

Main Methods:

  • Analysis of clinical, radiographic, CT, and MRI data from 64 histopathologically or genetically confirmed ES patients.
  • Evaluation of tumor size, local extension, signal intensity, enhancement patterns, and presence of metastases on various imaging modalities.

Main Results:

Related Experiment Videos

  • ES predominantly affects young males (mean age 17.9), with common locations in the pelvis and femur.
  • Radiographs/CT show spiculated periosteal reaction (50%) and cortical destruction (42%). MRI reveals a large soft tissue mass (67%) with variable enhancement.
  • Skip metastases (14%) and distant metastases (22%) are present at initial diagnosis.

    • Conclusions:

    • Ewing sarcoma (ES) is characterized by specific imaging features, including a large soft tissue mass and spiculated periosteal reaction.
    • Imaging findings on plain films, CT, and MRI aid in differentiating ES and assessing its extent.
    • Early detection of metastases is vital, as observed in a significant proportion of patients at initial presentation.