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Measurement of BK-polyomavirus Non-Coding Control Region Driven Transcriptional Activity Via Flow Cytometry
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Receptor-binding and oncogenic properties of polyoma viruses isolated from feral mice

John Carroll1, Dilip Dey, Lori Kreisman

  • 1Department of Pathology, Harvard Medical School, Boston, Massachusetts, United States of America.

Plos Pathogens
|December 19, 2007
PubMed
Summary

Wild mouse polyoma virus isolates share a common Vp1 type, identical to highly tumorigenic lab strains. This Vp1 type conserves oncogenic potential by maintaining specific receptor-binding properties, highlighting the need for neonatal immune protection.

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