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Updated: Jul 9, 2026

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Automation of Bio-Atomic Force Microscope Measurements on Hundreds of C. albicans Cells
Published on: April 2, 2021
Increases in SLT2 expression and chitin content are associated with incomplete killing of Candida glabrata by
Jason M Cota1, Jodi L Grabinski, Robert L Talbert
1University of Texas at Austin College of Pharmacy, UTHSCSA, PERC MSC 6220, 7703 Floyd Curl Drive, San Antonio, TX 78229, USA.
Antimicrobial Agents and Chemotherapy
|December 19, 2007
Abstract:
Incomplete killing was observed for caspofungin against Candida glabrata, which was associated with increased SLT2 expression and elevated chitin content. In contrast, fungicidal activity and no chitin increase were observed in an isogenic Delta slt2 strain, suggesting a role for SLT2 and chitin production in the response of C. glabrata to caspofungin.

