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Updated: Jul 9, 2026
Establishment of a Simple and Effective Rat Model for Intraoperative Parathyroid Gland Imaging
Published on: August 17, 2022
The role of ultrasonography in parathyroid surgery
Bridget A Boudreaux1, J Scott Magnuson, Scott A Asher
1Division of Otolaryngology, Head and Neck Surgery, University of Alabama at Birmingham, Birmingham, AL 35294-0012, USA.
Objective:
To assess the role of high-resolution ultrasonography in the preoperative evaluation of patients with hyperparathyroidism.
Design:
Retrospective cohort.
Setting:
Tertiary care university hospital.
Patients:
Three hundred seventeen patients with hyperparathyroidism who underwent preoperative assessment with ultrasonography and/or sestamibi scan and surgical treatment between October 2003 and October 2006.
Main Outcome Measures:
Descriptive statistics of localization imaging studies and detection of concomitant thyroid disease in patients presenting with hyperparathyroidism.
Results:
Ultrasonography correctly localized the parathyroid adenoma(s) in 148 (69.4%) of the 229 patients with these lesions. Sestamibi scans correctly localized the parathyroid adenoma(s) in 133 (58.1%) of the 229 patients. The agreement between the 2 imaging procedures was moderate (kappa = 0.23; 95% confidence interval, 0.12-0.36). Of 317 patients with hyperparathyroidism, 96 (30.3%) had clinically significant concomitant thyroid disease requiring partial or total thyroidectomy. Histopathologic examination revealed benign thyroid disease in 80 (83.0%) of the 96 patients and thyroid carcinoma in 16 (16.6%).
Conclusion:
Ultrasonography is a useful tool in the preoperative evaluation of patients with hyperparathyroidism both for localization of parathyroid adenomas and for the diagnosis of concomitant thyroid disease.
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