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Updated: Jul 9, 2026

Antibody Transfection into Neurons as a Tool to Study Disease Pathogenesis
Published on: September 26, 2012
[Neuropathy, monoclonal gammopathy and autoantibodies: how to establish a link?]
1G-H Pitié-Salpêtrière, Centre de référence des maladies neuromusculaires, Service du Pr J.-Y. Delattre, 47-84, boulevard de l'Hôpital, 75651 Paris cedex 13, France. tanya.stojkovic@psl-ap-hp-paris.fr
Abstract:
Monoclonal gammopathies are frequently observed in subjects older than 50 years. Understanding the pathogenetic role of paraproteins in peripheral nervous system damage is a necessary step to establish a link between the monoclonal gammopathy and neuropathy. The clinical, electrophysiological, biological and histopathological features of these neuropathies related to paraproteins are important to ensure appropriate treatments.
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