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[Splenectomy in sarcoidosis].

R Christ1, K Buchali, H Eckert

  • 1Forschungsinstitut für Lungenkrankheiten und Tuberkulose, Berlin-Buch.

Zeitschrift Fur Erkrankungen Der Atmungsorgane
|January 1, 1991
PubMed
Summary
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Splenectomy may be indicated for sarcoidosis patients with splenomegaly and hypersplenism unresponsive to cortisone therapy. Post-surgery, sarcoidosis activity generally remains unchanged, though infection risk increases.

Area of Science:

  • Internal Medicine
  • Immunology
  • Gastroenterology

Context:

  • Sarcoidosis is a multisystem inflammatory disease.
  • Splenomegaly is a potential complication of sarcoidosis.
  • Hypersplenism can necessitate intervention in sarcoidosis patients.

Purpose:

  • To evaluate the outcomes of splenectomy in patients with sarcoidosis and splenomegaly.
  • To assess the impact of splenectomy on sarcoidosis activity.
  • To identify potential complications following splenectomy for sarcoidosis.

Summary:

  • This report details six cases of sarcoidosis with splenomegaly.
  • Splenectomy was performed due to hypersplenism, abdominal pain, and failed cortisone therapy.
  • Sarcoidosis activity generally remained stable post-splenectomy, with one case of overwhelming postsplenectomy infection (OPSI) noted.

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Impact:

  • Splenectomy can be a therapeutic option for symptomatic splenomegaly in sarcoidosis.
  • Monitoring for infection is crucial after splenectomy in sarcoidosis patients.
  • Long-term follow-up is necessary to assess sarcoidosis activity and potential complications.