Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Ophthalmic Drug Delivery Systems

Ophthalmic Drug Delivery Systems

Ophthalmic drug delivery faces major limitations due to poor absorption across the corneal membrane. This process is primarily driven by diffusion and is influenced by two main factors: the physicochemical properties of the drug and tear drainage. Most ophthalmic drugs, such as pilocarpine, epinephrine, atropine, and local anesthetics, are weak bases. They are typically formulated at an acidic pH to enhance chemical stability. However, this leads to high ionization, reducing their ability to...

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Binocular visual function of Japanese eyes with nondiffractive extended depth-of-focus intraocular lenses made of high water-content hydrophobic acrylic material.

Japanese journal of ophthalmology·2025

Same author

Clinical performance of a hydrophobic acrylic toric intraocular lens with a double C-loop haptics in Japanese patients.

Japanese journal of ophthalmology·2025

Same author

Early Clinical Results of a Newly Developed Continuous Range of Vision Intraocular Lens.

Ophthalmology and therapy·2025

Same author

Visual outcomes following high water-content hydrophobic acrylic trifocal intraocular lens implantation.

BMC ophthalmology·2024

Same author

Influence of Visual Field on Visual Acuity and Contrast Sensitivity in Open-Angle Glaucoma Eyes with Monofocal and Extended Depth-of-Focus Intraocular Lenses.

Ophthalmology and therapy·2024

Same author

Retinal Image Quality Through an Operating Microscope With Wavefront Shaping Extended Depth of Focus Intraocular Lens in Model Eye.

American journal of ophthalmology·2024

Search research articles

Related Experiment Video

Updated: Jul 9, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Ophthalmic viscosurgical devices.

Hiroko Bissen-Miyajima¹

¹Department of Ophthalmology, Tokyo Dental College Suidobashi Hospital, Tokyo, Japan. bissen@tdc.ac.jp

Current Opinion in Ophthalmology

|December 20, 2007

Summary

This summary is machine-generated.

Ophthalmic viscosurgical devices (OVDs) offer expanded uses in anterior segment surgery. Careful selection and complete removal of OVDs are crucial for improving surgical outcomes and preventing complications like increased intraocular pressure.

Related Experiment Videos

Last Updated: Jul 9, 2026

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Rotating the Intraocular Lens to Prevent Posterior Capsular Opacification in Cataract Surgeries

Published on: July 7, 2023

Area of Science:

Ophthalmology
Surgical Technology

Background:

Ophthalmic viscosurgical devices (OVDs) were initially developed to maintain intraocular space during lens implantation.
The evolution of OVDs has led to expanded indications in anterior segment surgery.

Purpose of the Study:

To review the expanded indications and characteristics of newly developed ophthalmic viscosurgical devices.
To discuss the specific uses, potential complications, and prevention strategies associated with OVDs in anterior segment surgery.

Main Methods:

Comparative analysis of OVD retention capabilities for corneal endothelium protection during phacoemulsification.
Review of OVD properties for pupil enlargement and stabilization in specific surgical scenarios.
Discussion of complications and their management, emphasizing complete OVD removal.

Main Results:

OVDs protect the corneal endothelium, with varying retention abilities during phacoemulsification.
Specific OVDs are effective for managing small pupils and intraoperative floppy iris syndrome.
Postoperative intraocular pressure elevation is linked to incomplete OVD removal; wound burns can be prevented by fluid space creation.

Conclusions:

Considering the rheologic properties of different OVDs is essential for optimal surgical performance.
Appropriate selection and complete removal of OVDs enhance surgical outcomes and patient safety.