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Murine Oropharyngeal Aspiration Model of Ventilator-associated and Hospital-acquired Bacterial Pneumonia
Published on: June 28, 2018
Acinetobacter pneumonia: a review
Joshua D Hartzell1, Andrew S Kim, Mark G Kortepeter
1Uniformed Services University of the Health Sciences, Bethesda, Maryland, USA. Joshua.Hartzell@na.amedd.army.mil
Abstract:
Acinetobacter species are becoming a major cause of nosocomial infections, including hospital-acquired and ventilator-associated pneumonia. Acinetobacter species have become increasingly resistant to antibiotics over the past several years and currently present a significant challenge in treating these infections. Physicians now rely on older agents, such as polymyxins (colistin), for treatment. This paper reviews the epidemiology, treatment, and prevention of this emerging pathogen.
Insights
Acinetobacter species cause serious hospital infections and are increasingly resistant to antibiotics. Treatment now often relies on older drugs like polymyxins (colistin).
Area of Science:
- Microbiology
- Infectious Diseases
- Public Health
Background:
- Acinetobacter species are a growing cause of nosocomial infections.
- These include hospital-acquired pneumonia and ventilator-associated pneumonia.
- Increasing antibiotic resistance in Acinetobacter poses a significant treatment challenge.
Purpose of the Study:
- To review the epidemiology of Acinetobacter infections.
- To discuss current treatment strategies for Acinetobacter infections.
- To outline prevention methods for Acinetobacter infections.
Main Methods:
- Literature review of epidemiology.
- Analysis of treatment options.
- Summary of prevention guidelines.
Main Results:
- Acinetobacter is a significant nosocomial pathogen.
- Antibiotic resistance is a major concern.
- Polymyxins (colistin) are often used for treatment.
Conclusions:
- Effective management requires understanding epidemiology.
- Treatment relies on older antibiotics due to resistance.
- Prevention strategies are crucial to control spread.
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