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Related Experiment Video

Updated: Jul 9, 2026

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

A new twIst: two-step iterative shrinkage/thresholding algorithms for image restoration.

José M Bioucas-Dias1, Mario A T Figueiredo

  • 1Instituto de Telecomunicações and the Instituto Superior Técnico, Technical University of Lisbon, 1049-001 Lisboa, Portugal. jose.bioucas@lx.it.pt

IEEE Transactions on Image Processing : a Publication of the IEEE Signal Processing Society
|December 21, 2007
PubMed
Summary

Two-step iterative shrinkage/thresholding (TwIST) algorithms accelerate convergence for ill-posed inverse problems in image restoration. These methods offer significant speedups over standard IST algorithms, even for non-invertible operators.

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Area of Science:

  • Applied Mathematics
  • Image Processing
  • Optimization

Background:

  • Iterative shrinkage/thresholding (IST) algorithms are used for convex optimization in image restoration and linear inverse problems.
  • The convergence rate of IST algorithms is limited by the condition number of the linear observation operator, especially for ill-posed problems.

Purpose of the Study:

  • Introduce two-step IST (TwIST) algorithms to improve convergence speed for ill-conditioned inverse problems.
  • Develop a monotonic version (MTwIST) for non-invertible operators.

Main Methods:

  • Developed TwIST algorithms by modifying the iterative steps of standard IST.
  • Introduced a monotonic variant (MTwIST) to handle non-invertible observation operators.
  • Analyzed convergence properties for various nonquadratic convex regularizers, including total variation and Besov norms.

Related Experiment Videos

Last Updated: Jul 9, 2026

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures
07:05

Area-based Image Analysis Algorithm for Quantification of Macrophage-fibroblast Cocultures

Published on: February 15, 2022

Main Results:

  • TwIST algorithms demonstrate significantly faster convergence rates compared to IST for ill-conditioned problems.
  • TwIST algorithms are shown to converge to a minimizer for a range of parameters and regularizers.
  • MTwIST shows comparable speed gains to IST experimentally, despite theoretical convergence not being proven for non-invertible operators.

Conclusions:

  • TwIST algorithms provide a substantial improvement in convergence speed for image restoration and linear inverse problems.
  • MTwIST offers a promising approach for handling non-invertible operators in these applications.
  • The proposed methods are validated through experimental results in image deconvolution and restoration with missing samples.