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Related Concept Videos

Obesity01:24

Obesity

The Body Mass Index (BMI) is a numerical value derived from a person's weight and height, used to categorize individuals into weight ranges. It is calculated using the formula: weight in kilograms divided by height in meters squared. Obesity is a health condition characterized by excessive accumulation of adipose tissue that poses health risks, often diagnosed with a BMI ≥ 30. This excess fat storage occurs when surplus dietary calories are converted into triglycerides and stored in adipocytes...
Binge Eating Disorders01:23

Binge Eating Disorders

Binge eating disorder is a significant mental health condition characterized by recurrent episodes of excessive food consumption within a short period, accompanied by a perceived loss of control over eating behavior. Unlike occasional overeating, binge eating disorder is marked by distressing emotions such as guilt, shame, and anxiety following binge episodes. The disorder affects individuals across different ages and backgrounds, with profound implications for physical and psychological...
Drug Dosing: Obese Patients01:21

Drug Dosing: Obese Patients

In the United States, obesity is a prominent concern. It is linked to heightened mortality rates due to increased occurrences of conditions such as hypertension, atherosclerosis, coronary artery disease, and diabetes compared to nonobese individuals. A patient is classified as obese if their actual body weight surpasses the ideal or desirable body weight by 20%, based on Metropolitan Life Insurance Company data. Ideal body weights consider average weights and heights for males and females...
Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion01:20

Pharmacokinetics in Obese Patients: Drug Metabolism and Excretion

Drug metabolism, a critical process in the liver, involves two primary phases: Phase I reactions and Phase II conjugation. Obesity introduces significant alterations in this metabolic process, primarily due to fatty infiltration of the liver, leading to conditions such as nonalcoholic fatty liver disease (NAFLD). This condition can modify the activities of both Phase I and II enzymes, impacting how drugs are metabolized in obese patients.Phase I metabolism sees variable effects across...
Pharmacokinetics in Obese Patients: Drug Absorption and Distribution01:25

Pharmacokinetics in Obese Patients: Drug Absorption and Distribution

Obesity significantly alters the pharmacokinetic processes of drug absorption and distribution, presenting unique challenges in medical treatment. The increased fat tissue and decreased lean muscle in obese individuals can significantly affect how drugs are absorbed into the body and distributed across different tissues. This alteration can lead to variances in the effectiveness and safety of medications, necessitating adjustments in dosing or drug selection for obese patients.One notable...
Stress Prevention and Stress Management Techniques IV01:26

Stress Prevention and Stress Management Techniques IV

Stress often leads to unhealthy habits like smoking, excessive drinking, and overeating, which offer short-term relief but ultimately increase long-term health risks. These behaviors create a cycle that temporarily lowers stress levels but can result in severe long-term health consequences. Breaking these habits is essential to reduce the risk of chronic diseases and improve overall well-being. Three primary changes that support better health include quitting smoking, reducing alcohol intake,...

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Updated: Jul 9, 2026

Multidisciplinary Approach to Obesity Management: A Case Report
05:10

Multidisciplinary Approach to Obesity Management: A Case Report

Published on: May 30, 2025

Seeing obesity as a systems problem.

Barry Newell1, Katrina Proust, Robert Dyball

  • 1Fenner School of Environment and Society, The Australian National University. barry.newell@anu.edu.au

New South Wales Public Health Bulletin
|December 21, 2007
PubMed
Summary

The obesity epidemic may be driven by complex feedback systems involving human and environmental factors. A systems approach, analyzing these interactions, is proposed to manage this persistent global health challenge.

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Area of Science:

  • Public Health
  • Systems Science
  • Behavioral Science

Background:

  • Obesity is a global epidemic that has proven resistant to conventional interventions.
  • Persistent health challenges often indicate underlying feedback system dynamics.
  • Understanding these systems is crucial for developing effective solutions.

Purpose of the Study:

  • To investigate the role of feedback systems in the obesity epidemic.
  • To explore the interplay between human and environmental factors contributing to obesity.
  • To propose a systems approach for managing obesity.

Main Methods:

  • Review of systems analysis principles.
  • Conceptual framework development for human-environment interactions.
  • Identification of feedback mechanisms in obesity.

Main Results:

  • Feedback systems significantly influence the persistence of obesity.
  • A comprehensive analysis of human and environmental factors is necessary.
  • A systems approach offers a novel strategy for obesity management.

Conclusions:

  • The obesity epidemic can be better understood and managed through a systems perspective.
  • Interventions should consider the complex interactions within human-environment systems.
  • Four guiding principles for managing such complex systems are presented.