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Updated: Jul 9, 2026

Building Up Skin Models for Numerous Applications - from Two-Dimensional (2D) Monoculture to Three-Dimensional (3D) Multiculture
Published on: October 20, 2023
Protection one cell thick
John T Chang1, Steven L Reiner
1Abramson Family Cancer Research Institute and Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Abstract:
Specific immunity is a layer of defense exquisitely broad, terrifyingly thin, and yet remarkably durable on challenge. In this issue of Immunity, Stemberger et al. (2007) now take this concept to its logical extreme by offering evidence that expenditure of a single lymphocyte yields its own replenishment.
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