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Related Experiment Video

Updated: Jul 9, 2026

Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis

Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis

Published on: September 20, 2024

Faropenem medoxomil.

Jacob P Gettig¹, Christopher W Crank, Alexander H Philbrick

¹Pharmacy Practice, Midwestern University Chicago College of Pharmacy, Downers Grove, IL 60515, USA. jgetti@midwestern.edu

The Annals of Pharmacotherapy

|December 21, 2007

Summary

Faropenem medoxomil shows strong in vitro activity against respiratory pathogens and is effective for community-acquired infections. Further research is ongoing to clarify its role in antimicrobial therapy.

Area of Science:

Microbiology
Pharmacology
Infectious Diseases

Background:

Faropenem medoxomil is a novel penem antibiotic.
Understanding its profile is crucial for clinical application.

Purpose of the Study:

To review literature on faropenem medoxomil's in vitro activity, pharmacokinetics, in vivo efficacy, and safety.
To assess its potential as an antimicrobial agent.

Main Methods:

Comprehensive literature search of MEDLINE/PubMed and International Pharmaceutical Abstracts through July 2007.
Inclusion of published reports and abstracts without subsequent full publications.
Exclusion of English-language articles.

Main Results:

Excellent in vitro activity against respiratory pathogens, aerobic gram-positive, and anaerobic organisms; reserved activity against gram-negative organisms.

Related Experiment Videos

Last Updated: Jul 9, 2026

Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis

Development of a Polymicrobial Colony Biofilm Model to Test Antimicrobials in Cystic Fibrosis

Published on: September 20, 2024

Demonstrated noninferiority in clinical trials for sinusitis, pneumonia, bronchitis exacerbations, and skin infections.

Minimal adverse events, primarily nausea, vomiting, and diarrhea.

Conclusions:

Faropenem medoxomil exhibits potent activity against key pathogens relevant to community-acquired infections.
Efficacy is supported by clinical trial data, though its therapeutic niche requires further definition.
Ongoing studies aim to address regulatory concerns and solidify its antimicrobial role.