Related Experiment Video
Updated: Jul 9, 2026

Non-invasive Assessment of Microvascular and Endothelial Function
Published on: January 29, 2013
[Comparison of cardiovascular risk factors between normotension and prehypertension]
1Korea Association of Health Promotion, Seoul, Korea. cellonah@hanmail.net
Insights
Individuals with prehypertension show higher cardiovascular disease risk factors like elevated BMI and triglycerides compared to normotensive individuals. Age, BMI, and triglyceride levels are key determinants of prehypertension.
Area of Science:
- Cardiology
- Public Health
- Preventive Medicine
Background:
- Prehypertension increases cardiovascular disease (CVD) risk more than normal blood pressure.
- Understanding risk factors in prehypertension is crucial for early intervention.
Purpose of the Study:
- Investigate CVD risk factor differences between normotensive and prehypertensive groups.
- Identify key determinants of prehypertension.
Main Methods:
- Compared CVD risk factors in 3,732 normotensive and 676 prehypertensive individuals.
- Analyzed age, BMI, glucose, lipids, hsCRP, Lp(a), and WBC counts.
Main Results:
- Prehypertensive group had higher age, BMI, fasting glucose, triglyceride, and total cholesterol.
- Females in the prehypertensive group showed higher LDL-C and lower HDL-C.
- Age, BMI, and triglyceride levels determined prehypertension.
Conclusions:
- Significant differences in CVD risk factors exist between normotensive and prehypertensive individuals.
- Prehypertension is associated with specific metabolic and demographic factors.
Background:
The individuals with prehypertension are known to progress to hypertension, one of the risk factors of cardiovascular disease, more readily than the group of normal blood pressure. This study was performed to investigate the differences in the risk factors of cardiovascular disease between normotensive and prehypertensive groups, and to identify the determinants of prehypertension.
Methods:
Normotensive (N=3,732) and prehypertensive individuals (N=676) were selected from the people who underwent routine medical checkups at the Health Promotion Center (Seoul, Korea). The age, body mass index (BMI), fasting blood glucose, total cholesterol, triglyceride, LDL-cholesterol (C), HDL-C, high sensitivity C-reactive protein (hsCRP), lipoprotein(a) [Lp(a)], and the number of white blood cell were compared between the normotensive and prehypertensive groups.
Results:
The age, BMI, fasting blood glucose, triglyceride, and total cholesterol were higher in the males and females in the prehypertensive group than in the normotensive group. LDL-C, however, was higher and HDL-C was lower in the females in the prehypertensive group than in the normotensive group. The determinants of prehypertension were found to be age, BMI, and triglyceride.
Conclusions:
There were differences in the risk factors of cardiovascular disease between the prehypertensive and normotensive groups.
Related Concept Videos
Hypertension II: Pathophysiology
Hypertension and Regulation of Blood Pressure
Hypertension III: Clinical Manifestations and Diagnostic Studies
Hypertension I: Introduction
Alterations in Blood Pressure
Hypertension (High blood pressure)
Hypertension occurs when blood pressure readings consistently exceed the normal range. It is diagnosed when systolic blood pressure (the top number, indicating pressure while the heart beats)...
Factors affecting Blood pressure
Physiological Factors:
