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Related Concept Videos

Genomic Imprinting and Inheritance02:30

Genomic Imprinting and Inheritance

Diploid organisms inherit genetic material through chromosomes from both parents. Copies of the same gene are known as alleles. In most cases, both alleles are simultaneously expressed and allow various cellular processes to function optimally. If one of the alleles is missing or mutated, the expression of the other allele can compensate; however, this is not true for all genes.
The expression of some genes depends on which parent passed the gene to the offspring, through a phenomenon known as...
Imprinting01:22

Imprinting

Behavioral imprinting is observed in some newborn animals and occurs when they develop strong and specific attachments to another animal (usually a parent) following brief, early-life exposures. Offspring imprint onto parents within a brief period after birth or hatching; this time window is called the critical period. Once imprinting occurs, the bond established between the parents and their offspring is usually long-lasting.
Brain Imaging01:14

Brain Imaging

Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans),  magnetic resonance imaging (MRI),  functional magnetic resonance imaging (fMRI), and Transcranial Magnetic Stimulation (TMS).

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Related Experiment Video

Updated: Jul 9, 2026

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What are imprinted genes doing in the brain?

William Davies1, Anthony R Isles, Trevor Humby

  • 1Behavioral Genetics Group, Department of Psychological Medicine and School of Psychology, School of Medicine, University of Cardiff, Cardiff, Wales, UK. daviesw4@cardiff.ac.uk

Epigenetics
|December 21, 2007
PubMed
Summary

Genomic imprinting, a process where genes are expressed based on parental origin, plays a role in brain function and behavior. Further research is needed to understand its mechanisms and implications for neurological diseases.

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Area of Science:

  • Genomics
  • Neuroscience
  • Evolutionary Biology

Background:

  • Genomic imprinting involves parent-specific gene expression.
  • Evidence for brain-expressed imprinted genes is growing.
  • Understanding their function in the brain is crucial.

Purpose of the Study:

  • Investigate the roles of imprinted genes in brain function.
  • Reconcile imprinted gene action with evolutionary theories.
  • Explore the link between imprinting and neurological diseases.

Main Methods:

  • Review of existing evidence on brain-imprinted genes.
  • Identification of key research questions.
  • Highlighting the need for interdisciplinary collaboration.

Main Results:

  • Imprinted genes can influence diverse behaviors through brain mechanisms.
  • Imprinting may contribute to the risk of mental and neurological disorders.
  • A website (www.bgg.cardiff.ac.uk/imprinted_tables/index.html) provides information.

Conclusions:

  • Significant research gaps exist in understanding brain-imprinted genes.
  • Key questions involve molecular organization, neurodevelopmental dependence, epigenetic interactions, and adaptive significance.
  • Interdisciplinary efforts are essential to advance the field.