Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Vitiligo and cutaneous melanoma. A case study.

K U Schallreuter1, C Levenig, J Berger

  • 1Department of Dermatology, University of Hamburg, FRG.

Dermatologica
|January 1, 1991
PubMed
Summary

Vitiligo, a depigmentation disorder, is 7-10 times more common in melanoma patients. Patients with vitiligo have a significantly higher prevalence of melanoma, suggesting thorough skin cancer screening.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Comorbidity of chronic pain and fatigue : Common mechanisms, common treatment steps?]

Schmerz (Berlin, Germany)·2025
Same author

[Screening instruments: more light than shade].

Schmerz (Berlin, Germany)·2018
Same author

[Psychosocial risk factors for chronic back pain in the general population and in competitive sports : From theory to clinical screening-a review from the MiSpEx network].

Schmerz (Berlin, Germany)·2018
Same author

Rolipram does not normalize very long-chain fatty acid levels in adrenoleukodystrophy protein-deficient fibroblasts and mice.

Journal of inherited metabolic disease·2000
Same author

New insights into p53 regulation and gene therapy for cancer.

Biochemical pharmacology·2000
Same author

CFU-Mk content of immunoselected CD34+ peripheral blood progenitor cells, evaluated with an adapted serum-free methylcellulose assay, is predictive of platelet lineage reconstitution in children with solid tumors.

Journal of hematotherapy & stem cell research·2000

Area of Science:

  • Dermatology
  • Oncology
  • Immunology

Background:

  • Vitiligo is a depigmentation disorder with an unknown etiology.
  • Melanoma is a serious form of skin cancer.
  • The relationship between vitiligo and melanoma requires further investigation.

Purpose of the Study:

  • To determine the prevalence of vitiligo in melanoma patients.
  • To investigate the temporal relationship between vitiligo and melanoma onset.
  • To assess the association between melanoma risk factors and vitiligo prevalence.

Main Methods:

  • Retrospective analysis of 623 melanoma patients in North Germany.
  • Comparison of vitiligo prevalence in melanoma patients versus the general population.
  • Reverse analysis to determine melanoma prevalence in vitiligo patients.

Main Results:

  • Vitiligo was found in 3.7% of melanoma patients, a 7-10 fold increase compared to the general population.
  • Vitiligo prevalence correlated with melanoma risk factors like tumor thickness and location.
  • Patients with vitiligo exhibited a 180-fold higher prevalence of melanoma.

Conclusions:

  • There is a strong association between vitiligo and melanoma.
  • Patients with vitiligo should undergo thorough screening for primary melanoma.
  • Further research into the pathogenetic links between vitiligo and melanoma is warranted.

Related Experiment Videos