Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Atomic Force Microscopy01:08

Atomic Force Microscopy

Atomic force microscopy (AFM) is a type of scanning probe microscopy that can analyze topographic details of various specimens like ceramics, glass, polymers, and biological samples. AFM offers over 1000 times more resolution than the optical imaging system. Images generated from AFM are three-dimensional surface profiles, offering an advantage over the flat, two-dimensional images from other imaging techniques.
The AFM Probe
The probe is regarded as the heart of any AFM setup and comprises the...
Capillary Electrophoresis: Instrumentation01:20

Capillary Electrophoresis: Instrumentation

Capillary electrophoresis instrumentation typically consists of several key components. A high-voltage power supply generates the electric field necessary for the separation by connecting to an anode (the positively charged electrode) and a cathode (the negatively charged electrode) located in buffer reservoirs at each end of the capillary tube. The system includes a sample vial, a fused silica capillary tube coated with polyimide for mechanical strength through which the sample components...
Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)01:15

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT)

Insensitive Nuclei Enhanced by Polarization Transfer (INEPT) is an advanced Nuclear Magnetic Resonance (NMR) technique specifically designed to detect and enhance the signals of low-abundance nuclei, such as carbon-13 and nitrogen-15, in small molecules. The fundamental principle behind INEPT is the transfer of polarization from a more abundant and highly polarizable nucleus, typically hydrogen-1, to the low-abundance nucleus of interest. This process effectively boosts the NMR signal of the...
Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

3D-printed setup for ocular drug delivery evaluation on ex vivo porcine whole eye.

Scientific reports·2025
Same author

Assessing gut barrier integrity and reproductive performance following pre-mating oral administration of solid-lipid-nanoparticles designed for drug delivery.

Frontiers in toxicology·2025
Same author

Design of liposomal nanocarriers with a potential for combined dexamethasone and bevacizumab delivery to the eye.

International journal of pharmaceutics·2024
Same author

Advanced materials - Food grade melatonin-loaded Lipid Surfactant Submicron Particles (LSSP)-environmental impacts.

The Science of the total environment·2023
Same author

Nanoemulsion carriers for drug delivery: Assessment of environmental hazards.

Environmental pollution (Barking, Essex : 1987)·2023
Same author

Nanostructured Lipid Carriers for Enhanced Transscleral Delivery of Dexamethasone Acetate: Development, Ex Vivo Characterization and Multiphoton Microscopy Studies.

Pharmaceutics·2023

Related Experiment Video

Updated: Jul 9, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Nanovector.

Maria Rosa Gasco1, Paolo Gasco

  • 1Nanovector S.r.l., Via Livorno, 60-10144 Torino, Italy.

Nanomedicine (London, England)
|December 22, 2007
PubMed
Summary

This study showcases Nanovector's advanced lipid nanocarriers for drug delivery. Solid Lipid Nanoparticles demonstrate effective cell internalization and targeting to challenging areas like the brain and eye.

Area of Science:

  • Nanomedicine
  • Biotechnology
  • Pharmaceutical Sciences

Background:

  • Nanovector is an early pioneer in nanomedicine in Italy, established in 2001.
  • The company focuses on developing a proprietary technical platform for advanced drug delivery applications.
  • Extensive research has been conducted on lipid nanocarriers, microemulsions, and Solid Lipid Nanoparticles (SLNs).

Purpose of the Study:

  • To provide an overview of Nanovector's key research findings in drug delivery systems.
  • To highlight the potential of proprietary nanocarrier platforms for therapeutic development.
  • To evaluate the efficacy of SLNs as carriers for both hydrophobic and hydrophilic drugs across various administration routes.

Main Methods:

  • Testing of proprietary lipid nanocarriers, microemulsions, and Solid Lipid Nanoparticles (SLNs).

More Related Videos

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
09:53

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge

Published on: June 15, 2018

Related Experiment Videos

Last Updated: Jul 9, 2026

Nanomanipulation of Single RNA Molecules by Optical Tweezers
06:59

Nanomanipulation of Single RNA Molecules by Optical Tweezers

Published on: August 20, 2014

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution
11:55

Membrane Transport Processes Analyzed by a Highly Parallel Nanopore Chip System at Single Protein Resolution

Published on: August 16, 2016

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge
09:53

In Vivo Nanovector Delivery of a Heart-specific MicroRNA-sponge

Published on: June 15, 2018

  • Evaluation of drug delivery via intravenous, oral/duodenal, topical eye, and transdermal routes.
  • Assessment of in vivo cellular internalization, targeting capabilities, and mucosal penetration.
  • Main Results:

    • The nanocarrier delivery system platform exhibits promising and confirmed characteristics.
    • Solid Lipid Nanoparticles (SLNs) show potential as versatile carriers for diverse drug types.
    • Demonstrated rapid cellular internalization, in vivo targeting to the brain and posterior eye, and intestinal mucosa crossing.

    Conclusions:

    • The proprietary nanocarrier platform offers significant potential for drug delivery innovation.
    • SLNs enable enhanced drug administration, including transitioning from intravenous to oral routes.
    • Nanovector aims to leverage this technology for therapeutics addressing unmet medical needs.