Related Experiment Video
Updated: Jul 9, 2026

Tumor Treating Field Therapy in Combination with Bevacizumab for the Treatment of Recurrent Glioblastoma
Published on: October 27, 2014
Palliative treatment of poor prognosis patients with malignant gliomas
Mersiha Hadziahmetovic1, Simon S Lo, James W Clarke
1The Ohio State University College of Medicine, Ohio State University Medical Center, 300 West 10th Avenue, Ste 083A, Columbus, OH 43210, USA. mersiha.hadziahmetovic@osumc.edu
Abstract:
High-grade gliomas are the most commonly diagnosed malignant brain tumor in adults. Prognosis can be estimated by examining risk factors, including histology, age and performance status. Postoperative radiation therapy is associated with improved survival and standard treatment includes external beam radiotherapy to a dose of 60 Gy in 30-33 fractions. Patients with poor prognostic features have a more limited benefit from radiotherapy. This article reviews the current state of knowledge on risk stratification and analyzes strategies that can be employed to better individualize treatment for poor-prognosis patients.
Related Concept Videos
Treatment Resistant Cancers
Treatment Resistent Cancers

