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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients
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In Vitro and In Vivo Assessment of T, B and Myeloid Cells Suppressive Activity and Humoral Responses from Transplant Recipients

Published on: August 12, 2017

Bystander central memory but not effector memory CD8+ T cells suppress allograft rejection

Ni Wan1, Hehua Dai, Tao Wang

  • 1Center for Biomedical Research, University of Texas Health Center, Tyler, TX 75708, USA.

Journal of Immunology (Baltimore, Md. : 1950)
|December 22, 2007
PubMed
Summary

Bystander central memory (TCM) CD8+ T cells, not effector memory (TEM) cells, suppress immune responses and allograft rejection. These memory T cells migrate to lymph nodes, unlike TEM cells, to inhibit T cell activation and proliferation.

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