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Meningiomas in children.

Stephanie Greene1, Nathan Nair, Jeffrey G Ojemann

  • 1Department of Neurological Surgery, University of Washington School of Medicine, Seattle Children's Hospital and Regional Medical Center, Seattle, WA, USA. Greene1hinz@pol.net

Pediatric Neurosurgery
|December 22, 2007
PubMed
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Pediatric meningioma is rare. This study reviewed 20 cases, finding spontaneously arising tumors in younger patients and no recurrence in radiation-induced meningiomas.

Area of Science:

  • Pediatric neuro-oncology
  • Neurosurgery
  • Oncology

Background:

  • Meningiomas are tumors arising from the meninges.
  • Pediatric meningiomas are rare, necessitating further characterization.
  • Understanding risk factors and outcomes is crucial for this population.

Purpose of the Study:

  • To review the characteristics of pediatric meningioma patients.
  • To identify risk factors and outcomes associated with pediatric meningiomas.
  • To elucidate differences between spontaneously arising and risk-factor-associated meningiomas.

Main Methods:

  • Retrospective review of the Seattle Children's Hospital brain tumor database (1940-2004).
  • Identification and analysis of 20 pediatric patients diagnosed with meningioma.

Related Experiment Videos

  • Categorization based on etiology: radiation-induced, neurofibromatosis type 2, or spontaneously arising.

    • Main Results:

    • The median age of the 20 pediatric patients was 13 years.
    • Five patients had radiation-induced meningiomas, and five had neurofibromatosis type 2.
    • Ten patients had spontaneously arising meningiomas, with two being malignant.

    Conclusions:

    • Patients with spontaneously arising meningiomas were younger than those with known risk factors.
    • No recurrence was observed in pediatric patients with radiation-induced meningiomas.
    • Malignant meningiomas in pediatric patients were associated with mortality.