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Updated: Jul 9, 2026

Peptide-based Identification of Functional Motifs and their Binding Partners
Published on: June 30, 2013
HIV dynamics and immunosenescence
1Department of Environmental Science, Policy and Management, University of California, Berkeley, California, USA.
Abstract:
Three differential equations modelling HIV virion, and infected and uninfected immune-cell densities during acute and chronic phases of infection underlie in-vivo HIV viral dynamics models. Adding a fourth equation that simulates immunosenesence through the drawdown of a stem-cell reservoir permits the phase of full-blown AIDS to be incorporated in the model. This greatly enhances the utility of the model in designing interventions and explains why time-to-full-blown AIDS decreases with age at infection.
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