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PET/CT With [68Ga]-NOTA-FAP-2286 for Imaging of Tendon Injuries in Rat Achilles Tendon Injury Models
Published on: June 6, 2025
Baker cyst as seen on a PET/CT scan.
1Department of Radiology, Tufts-New England Medical Centre, Boston, MA 02111, USA. sbagga@tufts-nemc.org
Clinical Nuclear Medicine
|December 22, 2007
Summary
A multiple myeloma patient experienced knee pain, initially ignored. Imaging revealed a Baker cyst, not metastatic disease, highlighting the importance of investigating persistent symptoms.
Area of Science:
- Oncology
- Radiology
- Orthopedics
Background:
- Multiple myeloma is a cancer of plasma cells.
- Persistent, localized pain can be a challenging symptom in cancer patients.
- Positron Emission Tomography/Computed Tomography (PET/CT) is a key imaging modality for cancer staging.
Observation:
- A 48-year-old woman with a history of multiple myeloma presented with persistent right knee pain.
- A PET/CT scan showed no metastatic lesions but identified focal FDG uptake behind the knee.
- CT imaging revealed a fluid-density lesion consistent with a Baker cyst.
Findings:
- The focal FDG uptake in the knee was attributed to a Baker cyst, not myeloma metastasis.
- Previous MRI reports corroborated the presence of a Baker cyst.
- This case underscores the need for thorough investigation of seemingly minor symptoms in cancer patients.
Implications:
- Differentiating benign conditions from metastatic disease is crucial for accurate cancer management.
- Imaging findings must be interpreted in clinical context to avoid misdiagnosis.
- Persistent pain in cancer patients warrants comprehensive evaluation to rule out complications or unrelated pathologies.
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