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Related Experiment Video

Updated: Jul 9, 2026

Correction of Presbyopia by Monocular Bi-Aspheric Ablation Profile

Published on: September 20, 2024

Aberration-correcting effect of ThinOptX IOL.

M Ouchi¹, S Kinoshita

¹Department of Ophthalmology, Kyoto Prefectural University of Medicine, Kyoto, Japan. mouchi@ophth.kpu-m.ac.jp

Eye (London, England)

|December 22, 2007

Summary

The ThinOptX intraocular lens (IOL) demonstrated reduced spherical aberration and improved contrast sensitivity compared to the Acrysof lens in microincision cataract surgery. This suggests good visual function outcomes with the ThinOptX IOL.

Area of Science:

Ophthalmology
Biomedical Engineering
Optics

Background:

Cataract surgery aims to restore vision by replacing the clouded natural lens with an artificial intraocular lens (IOL).
Spherical aberration is a common optical imperfection that can affect visual quality after cataract surgery.
Microincision cataract surgery offers potential benefits like faster recovery, but lens choice is critical for optimal outcomes.

Purpose of the Study:

To evaluate and compare the spherical aberration and visual function after microincision cataract surgery using the ThinOptX rollable intraocular lens versus the Alcon Acrysof lens.
To assess the impact of IOL design on optical quality and contrast sensitivity.

Main Methods:

A prospective, comparative, and interventional case series involving 58 patients undergoing bimanual microphaco cataract surgery.

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The ThinOptX lens was implanted in one eye and an Alcon Acrysof lens in the fellow eye of each patient.

Spherical aberration (corneal, whole-eye, internal) and contrast sensitivity were measured one month post-surgery. Spherical aberration was also measured in artificial model eyes.

Main Results:

Eyes implanted with the ThinOptX lens showed significantly smaller whole-eye spherical aberration (P=0.03) and a trend towards smaller internal spherical aberration (P=0.07).
ThinOptX IOLs consistently induced negative internal spherical aberration, while Acrysof IOLs induced positive spherical aberration.
Slightly higher contrast sensitivity was observed across all cycles in eyes with the ThinOptX lens.

Conclusions:

The ThinOptX intraocular lens, designed for negative spherical aberration, resulted in reduced whole spherical aberrations and enhanced contrast sensitivity compared to the Acrysof lens.
Implantation of the ThinOptX IOL following microincision cataract surgery provides good visual function.
The study highlights the importance of IOL design in managing spherical aberration for improved visual outcomes.