Sponge biopsy in cancer diagnosis

Area of Science:

• Oncology
• Pathology
• Medical Diagnostics

Background:

• Cancer diagnosis often relies on invasive tissue sampling.
• Minimally invasive diagnostic methods are crucial for early detection and patient comfort.

Purpose of the Study:

• To introduce and evaluate a novel sponge biopsy method for cancer diagnosis.
• To compare the efficacy of sponge biopsy with traditional surgical biopsy.

Main Methods:

• A specialized sponge absorbs cells and tissue from mucous membranes or ulcerating lesions.
• Collected samples are processed as a tissue block for histological examination (fixing, embedding, cutting, staining).

Main Results:

• The sponge biopsy technique successfully collected cellular material for microscopic examination.
• Preliminary results indicate applicability in diagnosing cervical carcinoma.
• Comparison with surgical biopsy findings is presented.

Conclusions:

• Sponge biopsy offers a potentially less invasive approach to cancer diagnosis.
• The method is applicable to cervical cancer and may extend to other accessible mucous membrane lesions.