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[Granulocyte metabolic activity in chronic nonspecific lung diseases]
Terapevticheskii Arkhiv
|January 1, 1991
Abstract:
Biochemiluminescent (BCL) investigation of oxidative metabolism in patients suffering from chronic nonspecific lung diseases (CNLD) has shown activation of granulocyte metabolism measured by zymosan-dependent luminol-amplified chemiluminescence and the intensification of lipid peroxidation estimated by spontaneous serum BCL. At the same time H2O2-induced BCL was decreased, attesting to the abatement of antioxidative activity. The revealed imbalance of oxidative and antioxidative processes may be the pathogenic factor in CNLD development.