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Natural killer cells in meningiomas
1Department of Neurosurgery, Puerta de Hierro Clinic, Autonomous University, Madrid, Spain.
Histology and Histopathology
|July 1, 1991
Abstract:
A monoclonal antibody against the surface marker IOT-10 of natural killer (NK) cells was used to investigate the presence of these cells in a series of twenty intracranial meningiomas. In all of these tumours, IOT-10 positive NK cells were found in small numbers, mainly distributed among the tumor cells. Two recurrent tumors showed a relatively high number of immunostained cells. The data obtained in the present study suggest that a NK-cell-mediated immunological response can occur in meningioma tissue.