HLA and venous thrombosis: a prospective study

E Ivasková1, I Prerovský, M Riedel

  • 1Institute for Clinical and Experimental Medicine, Prague, Czechoslovakia.

Cor Et Vasa
|January 1, 1991
PubMed

The frequency of venous thrombosis diagnosed by the fibrinogen uptake test and ultrasound in relation to HLA typing was examined in a prospective study of 154 patients undergoing total hip replacement. The results demonstrate an association between venous thrombosis and the presence of HLA Cw4 and B35 (being in a linkage disequilibrium with Cw4) (Cw4 34.4% and B35 27.3%, relative risk 2.531 and 1.935 respectively). These results suggest that the presence of HLA Cw4 can be regarded as one of laboratory risk factors of venous thrombosis.

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