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Related Experiment Videos

Juvenile segmental muscular atrophy.

M Y Neufeld1, R Inzelberg, P Nisipeanu

  • 1Department of Neurology, Tel-Aviv Sourasky Medical Center, Israel.

Functional Neurology
|October 1, 1991
PubMed
Summary

Unilateral upper limb atrophy, a rare condition, was observed in two Middle Eastern patients. This study highlights its insidious onset and benign prognosis, emphasizing the need for clinical recognition.

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Area of Science:

  • Neurology
  • Clinical Neuroscience

Background:

  • Unilateral upper limb atrophy is a rare neurological condition.
  • Previously reported primarily in Asian populations, with isolated cases in Western countries.
  • No documented cases existed in the Middle East prior to this study.

Purpose of the Study:

  • To review the literature on unilateral upper limb atrophy.
  • To describe two novel cases presenting with brachial atrophy in the Middle East.
  • To emphasize the importance of recognizing this rare entity.

Main Methods:

  • Literature review on unilateral upper limb atrophy.
  • Clinical case study of two patients with brachial atrophy.
  • Electromyography (EMG) and neuroimaging (CT, myelography, MRI) were utilized.

Main Results:

  • Two cases presented with insidious onset unilateral upper limb atrophy.
  • Clinical and EMG findings indicated a localized anterior horn cell lesion in the cervical spinal cord.
  • Neuroimaging studies (CT, myelography, MRI) were normal in both patients.

Conclusions:

  • Unilateral upper limb atrophy is a rare entity with an insidious onset.
  • Clinical and EMG findings suggest localized cervical anterior horn cell lesions.
  • Recognition of this condition is crucial due to its benign outcome.

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