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[Hemo-rheologic disorders as risk factors of ischemic cerebral infarction]
1Katedry i Kliniki Neurologii AM, Poznaniu.
The problem of blood rheological abnormalities as risk factors for ischaemic stroke is only incompletely known. The blood rhreological++ parameters were measured in 35 patients with ischaemic stroke (groups: CS--completed stroke, TIA/RIND--transient brain ischaemia or reversible ischaemic neurological deficit) in the first 48 hours after the onset of the disease and then, for control, after 2-3 weeks. Persistence of abnormal rheological parameters of blood was observed, with increased plasma viscosity, reduced plasticity of erythrocytes, higher fibrinogen level, and increased erythrocyte aggregation 2-3 weeks after the onset of acute ischaemic stroke, which suggests their role as possible risk factors. In the group with completed stroke a significant increase of erythrocyte aggregation was noted 2-3 weeks after disease onset which may be connected with increased absorption of fibrinogen molecules on erythrocyte cell membrane.
The problem of blood rheological abnormalities as risk factors for ischaemic stroke is only incompletely known. The blood rhreological++ parameters were measured in 35 patients with ischaemic stroke (groups: CS--completed stroke, TIA/RIND--transient brain ischaemia or reversible ischaemic neurological deficit) in the first 48 hours after the onset of the disease and then, for control, after 2-3 weeks. Persistence of abnormal rheological parameters of blood was observed, with increased plasma viscosity, reduced plasticity of erythrocytes, higher fibrinogen level, and increased erythrocyte aggregation 2-3 weeks after the onset of acute ischaemic stroke, which suggests their role as possible risk factors. In the group with completed stroke a significant increase of erythrocyte aggregation was noted 2-3 weeks after disease onset which may be connected with increased absorption of fibrinogen molecules on erythrocyte cell membrane.