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[Transglottic carcinoma: a histopathological study of 64 cases]
1Second Hospital of Harbin Medical University.
Zhonghua Er Bi Yan Hou Ke Za Zhi
|January 1, 1991
Summary
Transglottic carcinoma, often considered advanced laryngeal cancer, presents with extensive tumors. This study suggests classifying these advanced lesions based on their laryngeal subsite for better understanding.
Area of Science:
- Otolaryngology
- Pathology
- Oncology
Context:
- Review of 64 surgically treated transglottic carcinoma cases.
- Analysis of anatomical sites and serial tumor sections.
- Evaluation of tumor staging and size.
Purpose:
- To investigate the characteristics of transglottic carcinoma.
- To determine if transglottic carcinoma represents an advanced stage of laryngeal cancer.
- To discuss the classification of laryngeal cancers.
Summary:
- 42 cases were supraglottic, 7 glottic, 5 subglottic, and 10 had unknown primary sites.
- 98.4% of cases were advanced stage (pT3-pT4), with 75% measuring >= 2 cm.
- Transglottic carcinoma exhibits paraglottic space spread and invasion of laryngeal frameworks.
Impact:
- Suggests transglottic carcinoma be viewed as an advanced laryngeal cancer.
- Highlights the pathological features of advanced laryngeal cancers.
- Recommends further discussion on classifying transglottic carcinoma as a distinct entity.