Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Paediatric renal transplantation--current perspectives.

H K Yap1

  • 1Department of Paediatrics, National University of Singapore.

The Journal of the Singapore Paediatric Society
|January 1, 1991
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Editorial: Kidney replacement therapy advances in children.

Frontiers in pediatrics·2022
Same author

Long-term outcomes with multi-targeted immunosuppressive protocol in children with severe proliferative lupus nephritis.

Lupus·2015
Same author

Genetic Interactions Between TRPC6 and NPHS1 Variants Affect Posttransplant Risk of Recurrent Focal Segmental Glomerulosclerosis.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons·2015
Same author

Good outcomes with mycophenolate-cyclosporine-based induction protocol in children with severe proliferative lupus nephritis.

Lupus·2010
Same author

Role of urinary screening programmes in children in the prevention of chronic kidney disease.

Annals of the Academy of Medicine, Singapore·2005
Same author

Algorithm to achieve prescribed dialysis adequacy targets for non-compliant children on automated peritoneal dialysis (APD).

Annals of the Academy of Medicine, Singapore·2005

Pediatric end-stage renal disease patients benefit from renal transplantation over chronic dialysis, which can impede growth and quality of life. Specialized pediatric transplant centers improve outcomes and psychosocial rehabilitation.

Area of Science:

  • Pediatric Nephrology
  • Transplant Surgery
  • Immunology

Background:

  • Chronic dialysis for pediatric end-stage renal disease (ESRD) presents challenges including impaired growth, bone disease, and reduced quality of life.
  • Renal transplantation offers pediatric ESRD patients a near-normal lifestyle with better long-term prospects for employment and family life.

Purpose of the Study:

  • To highlight the advantages of renal transplantation for children with end-stage renal disease compared to chronic dialysis.
  • To emphasize the critical role of specialized pediatric transplant facilities in optimizing patient and graft survival.

Main Methods:

  • Comparative analysis of outcomes between chronic dialysis and renal transplantation in pediatric ESRD patients.
  • Review of specific challenges in pediatric transplantation, including perioperative fluid balance, immune response, and immunosuppression pharmacokinetics.

Related Experiment Videos

Main Results:

  • Renal transplantation significantly improves patient and graft survival in children, especially when performed in centers with comprehensive pediatric facilities.
  • Specialized centers better manage age-related issues like heightened immune responsiveness and unique drug handling in children.

Conclusions:

  • Renal transplantation is the preferred treatment for pediatric ESRD, offering superior long-term outcomes and quality of life.
  • Addressing growth, development, and psychosocial aspects is crucial for the successful rehabilitation of pediatric transplant recipients.