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Muscle cell death. Ultrastructural differences between muscle cell necrosis and apoptosis
A Fidziańska1, A Kamińska, Z Glinka
1Department of Neurology, School of Medicine, Warsaw.
Abstract:
The morphology and incidence of muscle cell necrosis and apoptosis are presented. Necrosis which occurs as a massive tissue damage is structurally characterized by swelling of the muscle cell and disruption of cellular components. Apoptosis, on the other hand, is a process of active cellular self-destruction. It shows characteristic sequence of muscle cell shrinkage, which is ending in transformation of each muscle cell into compact apoptotic bodies that in turn are phagocytized by adjacent cells or macrophages.