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Magnesium content of mononuclear blood cells in newborn infants and its correlation with maternal magnesium status
G Lombardo1, G Di Pasquale, R Manganaro
1Institute of the Pediatric Clinic, University of Messina, Italy.
In 25 full-term infants at birth and in their mothers, we determined plasma and mononuclear blood cell (MBC) Mg levels in order to investigate the relationship between maternal and fetal Mg status. MBC isolation for Mg analysis was carried out with a Ficoll-Isopaque gradient which is commercially available in disposable tubes. There was no difference in the plasma and MBC Mg levels between infants and their mothers. Neonatal MBC Mg content was significantly correlated with maternal plasma Mg concentration. The data demonstrate that MBC Mg content does not present any difference on the basis of age and emphasize that the constitution of fetal Mg reserve depends on maternal plasma Mg concentration.
In 25 full-term infants at birth and in their mothers, we determined plasma and mononuclear blood cell (MBC) Mg levels in order to investigate the relationship between maternal and fetal Mg status. MBC isolation for Mg analysis was carried out with a Ficoll-Isopaque gradient which is commercially available in disposable tubes. There was no difference in the plasma and MBC Mg levels between infants and their mothers. Neonatal MBC Mg content was significantly correlated with maternal plasma Mg concentration. The data demonstrate that MBC Mg content does not present any difference on the basis of age and emphasize that the constitution of fetal Mg reserve depends on maternal plasma Mg concentration.