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[Systemic strongyloidiasis. Review].

L Chacín-Bonilla1

  • 1Instituto de Investigaciones Clínicas, Facultad de Medicina, Universidad del Zulia, Maracaibo, Venezuela.

Investigacion Clinica
|January 1, 1991
PubMed
Summary

Systemic strongyloidiasis, caused by Strongyloides stercoralis, is a dangerous opportunistic infection in immunocompromised individuals. Early diagnosis and prompt treatment with thiabendazole are crucial to prevent fatal outcomes.

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Area of Science:

  • Infectious Diseases
  • Parasitology
  • Immunology

Context:

  • Strongyloides stercoralis is endemic in Venezuela.
  • Systemic strongyloidiasis is an opportunistic infection.
  • Information on systemic strongyloidiasis is scarce, particularly in Venezuela.

Purpose:

  • To describe the clinical presentation, diagnosis, and treatment of systemic strongyloidiasis.
  • To highlight the importance of early diagnosis in at-risk patients.
  • To emphasize the need for increased awareness of this infection.

Summary:

  • Systemic strongyloidiasis presents with variable gastrointestinal and respiratory symptoms, potentially leading to paralytic ileus, respiratory insufficiency, sepsis, and meningitis.
  • Diagnosis involves identifying larvae in stool, duodenal/jejunal aspirates, sputum, and other body fluids like CSF and peritoneal fluid.
  • Prompt treatment with thiabendazole is effective, necessitating its consideration in at-risk, immunosuppressed patients.

Impact:

  • Highlights a neglected tropical disease with severe manifestations.
  • Emphasizes the diagnostic challenges and clinical importance of systemic strongyloidiasis.
  • Provides crucial information for clinicians managing immunocompromised patients in endemic areas.

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