[Genetic polymorphism of alpha 2HS-glycoprotein in the Han population in Chengdu]

The distribution of alpha 2HS-glycoprotein (AHSG) phenotype frequencies in the Han population in Chengdu was studied using polyacrylamide gel isoelectric focusing followed by immunofixation with rabbit anti-human AHSG serum. Two hundred eighty-six serum samples collected at random from unrelated individuals were phenotyped for AHSG. The distribution of AHSG phenotype frequencies was found to be AHSG 1 = 47.20%, AHSG 2 = 8.04% and AHSG 2 - 1 = 44.76%. The observed numbers agreed well with the expected numbers calculated on the basis of the Hardy-Weinberg equilibrium. The allele frequencies were estimated to be AHSG.1 = 0.6958 and AHSG.2 = 0.3042. The discrimination probability of AHSG is 0.5704 and the exclusion probability of parentage 0.1669.