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Updated: Aug 8, 2026

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Impression Cytology of the Lid Wiper Area
Published on: August 9, 2016
Modification of impression cytology for in-office use
C G Connor1, J B Campbell, W W Tirey
1Contact Lens Clinic, Southern College of Optometry, Memphis, TN 38104.
Abstract:
An in-office procedure for assessment of the conjunctival epithelium, goblet cells, mucin and immune cells is described. The collection of three samples from each eye greatly improves cell harvest and increases reproducibility of the technique called impression cytology. The protocol and its pitfalls are discussed as well as the numerous applications of impression cytology.

