Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Depression: Overview01:18

Depression: Overview

Depression is a prevalent mental illness marked by persistent sadness and lack of interest in previously enjoyable activities. It can take several forms, including major depression, persistent depressive disorder, and bipolar I and II disorders. Symptoms range from emotional changes like chronic worry to physical changes like sleep disturbances and suicidal thoughts. From a neurobiological perspective, depression is believed to be triggered by abnormalities in the brain's prefrontal cortex,...
Long-term Depression01:05

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Long-term Depression01:03

Long-term Depression

Long-term depression, or LTD, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTD is the process of synaptic weakening that occurs over time between pre and postsynaptic neuronal connections. The synaptic weakening of LTD works in opposition to synaptic strengthening by long-term potentiation (LTP) and together are the main mechanisms that underlie learning and memory.
Calcium Ion Concentration Mechanism
If over time, all...
Depressive Disorders: Etiology01:27

Depressive Disorders: Etiology

Depressive disorders result from a complex interplay of biological, psychological, and sociocultural factors, each contributing uniquely to the development and persistence of the condition. Understanding these factors provides critical insight into the multifaceted nature of depression.
Biological Factors in Depression
Biological predispositions significantly influence the risk of developing depressive disorders. Genetic studies highlight the role of variations in the serotonin transporter...
Depressive Disorders: MDD and Dysthymia01:27

Depressive Disorders: MDD and Dysthymia

Depressive disorders are a group of mental health conditions characterized by pervasive feelings of sadness, diminished pleasure in life, and a significant impact on daily functioning. These conditions are most prevalent in individuals during their 30s and affect women at twice the rate of men. Contrary to popular belief, younger individuals are generally more susceptible to these disorders than older adults. Two key types of depressive disorders include Major Depressive Disorder (MDD) and...
Community Based Intervention01:30

Community Based Intervention

Community-based interventions in mental health represent a paradigm shift from institution-centered care to treatments embedded within the fabric of local communities. By prioritizing inclusion and leveraging existing societal structures, this approach fosters a supportive environment conducive to addressing mental health challenges while promoting individual dignity and agency.
Foundations of Community Mental Health Programs
Central to the success of community-based interventions is the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pharmacotherapy for alcohol misuse: Views of patients, providers, and leaders in an Alaska Native healthcare system.

Journal of substance use and addiction treatment·2026
Same author

Understanding Risk Factors for Otitis Media in Rural Alaska Native Children: A Cohort Study.

Ear and hearing·2025
Same author

Assessing Environmental, Nutritional, and Genetic Factors for Otitis Media-Related Hearing Loss in Rural Alaska Native Children.

Ear and hearing·2025
Same author

Attitudes About Alcohol Misuse Among Alaska Native People in a Tribal Health Care System.

Journal of addiction medicine·2025
Same author

Making a Community Health Needs Assessment Participatory: A Case Study from an Alaska Native Health Care Organization.

American Indian and Alaska native mental health research (Online)·2025
Same author

Advancing genomics to improve health equity.

Nature genetics·2024

Related Experiment Video

Updated: Jul 8, 2026

Animal Models of Depression - Chronic Despair Model (CDM)
05:47

Animal Models of Depression - Chronic Despair Model (CDM)

Published on: September 23, 2021

The Southcentral Foundation depression collaborative.

Denise A Dillard1, Deborah Christopher

  • 1Research Department, Southcentral Foundation, Anchorage, Alaska 99508, USA ddillard@southcentralfoundation.com

International Journal of Circumpolar Health
|December 25, 2007
PubMed
Summary
This summary is machine-generated.

This study shows a primary care and behavioral health collaboration effectively treated depression in Alaska Native and American Indian patients. The program identified and managed depressive symptoms in individuals not previously diagnosed or seeking specialty care.

More Related Videos

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Related Experiment Videos

Last Updated: Jul 8, 2026

Animal Models of Depression - Chronic Despair Model (CDM)
05:47

Animal Models of Depression - Chronic Despair Model (CDM)

Published on: September 23, 2021

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method
07:12

Individualized rTMS Treatment for Depression using an fMRI-Based Targeting Method

Published on: August 2, 2021

Area of Science:

  • Public Health
  • Mental Health Services
  • Health Disparities

Background:

  • Depression is a significant health concern among Alaska Native and American Indian populations.
  • Limited access to specialty care can hinder effective depression treatment in these communities.

Purpose of the Study:

  • To describe a collaborative model between primary care and behavioral health clinics.
  • To evaluate the effectiveness of this collaboration in treating depression among Alaska Native and American Indian patients.

Main Methods:

  • Cross-sectional study design.
  • Utilized the Patient Health Questionnaire for depression screening (DSM-IV criteria).
  • Analyzed computerized medical records for descriptive data, including antidepressant prescription and service utilization.

Main Results:

  • 17.2% of screened patients (n=2,534) tested positive for depression.
  • 57% of positive cases received antidepressant prescriptions.
  • 55% of initially positive patients showed symptom improvement upon follow-up.
  • Less than half (42%) had received specialty behavioral health care or a mood disorder diagnosis in the prior year.

Conclusions:

  • The collaborative program successfully identified and treated depression in underserved Alaska Native and American Indian patients.
  • This model offers a potential strategy to address depression as a public health issue in these populations.
  • Further research is recommended to refine program improvement and contribute to health disparities literature.