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Procainamide-induced pseudo-obstruction in a diabetic patient
A M Peterson1, S D Conrad, J M Bell
1Department of Pharmacy, Hahnemann University, Philadelphia, PA.
DICP : the Annals of Pharmacotherapy
|December 1, 1991
Summary
Procainamide hydrochloride therapy can cause severe bowel pseudo-obstruction, especially in diabetic patients. This drug-induced gastrointestinal hypomotility resolved only after discontinuing procainamide.
Area of Science:
- Pharmacology
- Gastroenterology
- Internal Medicine
Background:
- Procainamide hydrochloride is an antiarrhythmic medication.
- Gastrointestinal pseudo-obstruction is a rare but serious condition characterized by symptoms of bowel obstruction without mechanical blockage.
- Drug-induced pseudo-obstruction can mimic other gastrointestinal disorders.