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MMsat--a database of potential micro- and minisatellites
Andrew Shelenkov1, Alexander Korotkov, Eugene Korotkov
1Bioinformatics Department of Bioengineering Centre of Russian Academy of Sciences, Prospect 60-tya Oktyabrya, 7/1, Room 303, 117312, Moscow, Russia. fallandar@gmail.com
Gene
|December 25, 2007
Summary
We introduce MMsat, a database of DNA sequences exhibiting significant latent periodicity. These sequences, with periods of 2-100 bases, are valuable for micro- and minisatellite research and PCR analysis.
Area of Science:
- Genomics
- Bioinformatics
- Molecular Biology
Background:
- DNA sequences often contain repetitive elements.
- Identifying periodic patterns is crucial for understanding genome organization and function.
- Latent periodicity in DNA can be indicative of micro- and minisatellites.
Purpose of the Study:
- To present MMsat, a novel database of DNA sequences with statistically significant latent periodicity.
- To catalog sequences with period lengths ranging from 2 to 100 bases.
- To facilitate research on micro- and minisatellites and their evolutionary significance.
Main Methods:
- Utilized an analytical method of information decomposition to detect periodicity.
- Sourced DNA sequences from the GenBank database.
- Analyzed the distribution, properties, and potential functions of the identified periodic sequences.
Main Results:
- Identified a substantial collection of DNA sequences exhibiting latent periodicity.
- Confirmed high statistical significance for the detected periodicity.
- Characterized sequences with period lengths between 2 and 100 bases.
Conclusions:
- The MMsat database provides a valuable resource for studying periodic DNA sequences.
- These sequences are potential candidates for micro- and minisatellites, useful in PCR analysis.
- Further investigation into the distribution, properties, and functions of this periodicity is warranted for evolutionary studies.
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