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Self-assembled monolayers: solidification of carbamazepine in Form II at an interface
Florence Quist1, Jonathan Mooney, Ashok K Kakkar
1Department of Chemistry, McGill University, Montreal, Quebec H3A 2K6, Canada.
Abstract:
A self-assembled monolayer incorporating well-spaced biphenyl moieties initiates solidification of carbamazepine at its interface. A detailed analysis of the resulting crystals using X-ray powder diffraction, FTIR-ATR as well as thermomicroscopy, indicates a preference for its crystallization in trigonal (Form II) polymorph.
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