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Oncogenic Gene Fusion Detection Using Anchored Multiplex Polymerase Chain Reaction Followed by Next Generation Sequencing
Published on: July 5, 2019
[Chronic Myelogenous Leukemia with a Variant Philadelphia Translocation: t(11;22)(q25;q11.2).]
Han Sung Kim1, Hyoun Chan Cho, Sun Hee Kim
1Department of Laboratory Medicine, Hallym University College of Medicine, Anyang, Korea. moonys@inha.ac.kr.
The Korean Journal of Laboratory Medicine
|December 25, 2007
Abstract:
We report a case of chronic myelogenous leukemia displaying a variant Philadelphia translocation t(11;22)(q25;q11.2). Breakpoint 11q25 has not previously been reported. Reverse transcriptase polymerase chain reaction and fluorescence in-situ hybridization demonstrated the BCR/ABL rearrangement.
