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Updated: Jul 8, 2026
Preparation, Procedures and Evaluation of Platelet-Rich Plasma Injection in the Treatment of Knee Osteoarthritis
Published on: January 4, 2019
[Utility of platelet-rich plasma and growth factors bone in the bone defects. Regional Hospital Lic. Adolfo López
Trinidad Ramón Mendieta Archundia1, Juan Carlos Alvarado Soriano, Jorge Negrete Corona
1Hospital Regional Lic. Adolfo López Mateos ISSSTE, México, D.F.
Introduction:
The platelet-rich plasma is a concentrated of platelets with the presence of growth factors and proteins that serve as osteoconducer matrix for bone formation. We present the results obtained with the use of platelet-rich plasma and a hydroxyapatite and bovine collagen graft in the management of bone defects.
Material And Methods:
We studied eight patients with bone defects, treated surgically in whom platelet rich plasma and a hydroxyapatite and bovine collagen graft was used, with clinical and radiographic follow-up at 2, 4, 6, 10 and 18 weeks after surgery.
Results:
Starting on week 7 since surgery, evidence of osteointegration and bone callus formation, during the weeks 10 and 14 most cases showed bone consolidation. A case without consolidation through week 18.
Discussion:
The immediate response of the body tissue damaged is the accumulation of a large number of activated platelets, which release their granules and growth factors that promote the regeneration of tissues. It is possible to obtain platelet-rich plasma and accelerating the process of bone regeneration. Our study shows beneficial results with the use of platelet-rich plasma.
