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Tea catechin consumption reduces circulating oxidized low-density lipoprotein.
Shigenobu Inami1, Masamichi Takano, Masanori Yamamoto
1Department of Internal Medicine, Chiba-Hokusoh Hospital, Nippon Medical School, Chiba, Japan.
International Heart Journal
|December 28, 2007
Summary
Green tea
Area of Science:
- Cardiovascular Health
- Nutritional Science
- Biochemistry
Background:
- Green tea consumption is linked to reduced coronary artery disease risk.
- Catechin, a green tea antioxidant, may impact lipid oxidation.
- Oxidized low-density lipoprotein cholesterol (LDL-C) is implicated in atherosclerosis.
Purpose of the Study:
- To investigate the effect of catechin intake on lipid profiles.
- To assess catechin's impact on plasma oxidized LDL levels.
Main Methods:
- A randomized controlled trial with 40 healthy volunteers.
- Oral administration of 500 mg catechin daily for 4 weeks.
- Measurement of plasma lipid profiles and oxidized LDL via enzyme immunoassay.
Main Results:
- Plasma oxidized LDL significantly decreased post-catechin administration (P = 0.005).
- No significant changes observed in plasma LDL-C, triglyceride, or HDL-C levels.
- Catechin reduced oxidized LDL without altering LDL-C concentration.
Conclusions:
- Catechin intake effectively lowers plasma oxidized LDL levels.
- This reduction in oxidized LDL may explain green tea's cardiovascular benefits.
- Further research can explore catechin's role in preventing atherosclerosis.
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