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Angiosarcoma of the face and scalp
1Department of Dermatology, University of Leipzig, Germany.
International Journal of Dermatology
|December 1, 1991
Summary
Angiosarcoma of the face and scalp is a rare vascular cancer. Despite aggressive treatment, this aggressive cancer often leads to poor outcomes.
Area of Science:
- Oncology
- Dermatology
- Pathology
Background:
- Angiosarcoma is a rare malignant vascular tumor.
- Face and scalp angiosarcoma presents unique challenges due to anatomical location.
Purpose of the Study:
- To describe the clinical and histological features of angiosarcoma of the face and scalp.
- To evaluate treatment outcomes and disease progression in these patients.
Main Methods:
- Retrospective review of 12 patients diagnosed with angiosarcoma of the face and scalp.
- Analysis of clinical presentation, treatment modalities, and patient outcomes.
Main Results:
- The average age of affected patients was 71 years.
- Tumors presented as violaceous vascular nodules or plaques.
- Complications included ulceration, infection, bleeding, bone infiltration, and cachexia, leading to death.
- Histology showed a mix of benign-appearing hemangiomatous areas and solid sarcomatous areas.
- Metastases were not observed in any patient.
Conclusions:
- Early and extensive surgical excision is the preferred treatment.
- Despite surgery, the disease course is often relentless and fatal.
- Palliative radiation and polychemotherapy showed limited efficacy in controlling tumor progression.