Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Injectable Self-Healing Oxidized Hyaluronic Acid Hydrogel Remodels the Healing Microenvironment for Efficient Wound Closure.

Acta biomaterialia·2026
Same author

Development of Confocal Multispectral Imaging Using a Common Commercial Device and Application in a Healthy Aging Mouse Model.

Investigative ophthalmology & visual science·2026
Same author

Leveraging nanoparticle protein corona to advance plasma proteome profiling.

Nature communications·2026
Same author

A minimally invasive, scalable and reproducible neonatal rat model of severe focal brain injury.

Brain communications·2026
Same author

Astrocytic FABP5 drives non-cell-autonomous oligodendrocyte injury in multiple system atrophy by promoting TNF signaling and ferroptotic stress.

Redox biology·2026
Same author

Detailed Outer Retinal Assessment in Parkinson's Disease Using Directional OCT.

Investigative ophthalmology & visual science·2026

Related Experiment Video

Updated: Jul 8, 2026

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

Neural tissue engineering of the CNS using hydrogels.

David R Nisbet1, Kylie E Crompton, Malcolm K Horne

  • 1Department of Materials Engineering, Division of Biological Engineering, Monash University, Wellington Road, Clayton, VIC 3800, Australia.

Journal of Biomedical Materials Research. Part B, Applied Biomaterials
|December 29, 2007
PubMed
Summary

Central nervous system (CNS) regeneration is limited in adult mammals. This review explores hydrogel scaffolds and their modifications to promote nerve repair and CNS regeneration.

More Related Videos

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

Related Experiment Videos

Last Updated: Jul 8, 2026

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration
08:52

Three-dimensional Tissue Engineered Aligned Astrocyte Networks to Recapitulate Developmental Mechanisms and Facilitate Nervous System Regeneration

Published on: January 10, 2018

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling
10:45

Anatomically Inspired Three-dimensional Micro-tissue Engineered Neural Networks for Nervous System Reconstruction, Modulation, and Modeling

Published on: May 31, 2017

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation
09:19

Improved 3D Hydrogel Cultures of Primary Glial Cells for In Vitro Modelling of Neuroinflammation

Published on: December 8, 2017

Area of Science:

  • Biomaterials Science
  • Neuroscience
  • Regenerative Medicine

Background:

  • Current therapies offer limited capacity to halt central nervous system (CNS) damage or disease progression in adult mammals.
  • Successful regeneration of the CNS is hindered by inhibitory physical and chemical barriers and a lack of pro-regenerative cues.
  • Neural tissue engineering strategies aim to create supportive microenvironments for CNS repair.

Purpose of the Study:

  • To review the application of hydrogel scaffolds in neural tissue engineering.
  • To discuss physical and chemical modifications of hydrogels for promoting nerve regeneration.

Main Methods:

  • Review of existing literature on hydrogel scaffolds for CNS regeneration.
  • Analysis of modifications to hydrogel materials to enhance their regenerative potential.

Main Results:

  • Hydrogel scaffolds show promise in creating favorable microenvironments for CNS repair.
  • Specific physical and chemical modifications can enhance the efficacy of hydrogels in promoting nerve regeneration.

Conclusions:

  • Hydrogel scaffolds represent a viable strategy in neural tissue engineering for CNS repair.
  • Tailoring hydrogel properties is crucial for overcoming regeneration barriers and advancing CNS repair therapies.