Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Pulmonary Tuberculosis I

Pulmonary Tuberculosis I

Tuberculosis, often called TB, is a contagious illness primarily caused by Mycobacterium tuberculosis. It mainly affects the lung parenchyma but can also impact other body parts.
Causative Organism
The primary infectious agent causing tuberculosis is Mycobacterium tuberculosis, a slow-growing, acid-fast, aerobic rod that exhibits sensitivity to heat and ultraviolet light. Instances of Mycobacterium bovis and Mycobacterium avium contributing to the development of TB infection are rare.
Mode of...

Pulmonary Tuberculosis II

Pulmonary Tuberculosis II

Tuberculosis, or TB, is a bacterial infectious disease caused by Mycobacterium tuberculosis. While its primary impact is on the lungs, leading to pulmonary tuberculosis, it can also affect various other organs, a condition referred to as extrapulmonary tuberculosis.
Here is a detailed explanation of its pathophysiology:
Transmission: The process begins when a person inhales droplet nuclei containing M. tuberculosis. These are typically released into the air when an individual with pulmonary or...

Pulmonary Tuberculosis III

Pulmonary Tuberculosis III

Tuberculosis (TB) is a contagious infection primarily affecting the lung parenchyma but which can also affect other body parts. TB can be classified based on disease development, presentation, and the affected anatomical site.
The first classification is based on the development of the disease, and it includes the following categories:

Pulmonary Tuberculosis IV

Pulmonary Tuberculosis IV

Tuberculosis, more commonly referred to as TB, is an infectious disease stemming from Mycobacterium tuberculosis. While it primarily impacts the lungs, TB can also affect other body areas. Given its severity and global impact, timely and accurate diagnosis is crucial for controlling its spread and improving patient outcomes.
Several diagnostic approaches are used to detect TB. The conventional method is the Tuberculin Skin Test (TST), also known as the Mantoux test. However, this method has...

Pulmonary Tuberculosis V

Pulmonary Tuberculosis V

Medical management of tuberculosis (TB) patients involves a comprehensive approach that includes diagnosis, treatment, and monitoring. The specific strategies can vary depending on the type of tuberculosis (latent or active), the patient's overall health status, and other considerations.
Latent tuberculosis infection occurs when TB bacteria are present in a person's body, but are not causing illness or symptoms. It is not contagious, and preventive treatment is crucial to avoid the progression...

Tuberculosis

Tuberculosis

Tuberculosis (TB) remains a significant global health concern, primarily targeting the lungs and spreading through airborne transmission. Infection begins when aerosolized droplet nuclei, expelled by an individual with active TB, are inhaled by another person. These microscopic particles carry Mycobacterium tuberculosis, the causative agent of TB. Upon reaching the alveoli, the bacilli are engulfed by alveolar macrophages. However, due to their specialized lipid-rich cell wall, these pathogens...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Hydroxychloroquine dosing and toxicity: A real-world experience in Saudi Arabia of 63 patients.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society·2021

Same author

Incidence of posterior capsule opacification following phacoemulsification in patients with uveitis.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society·2021

Same author

Aqueous penetration of topical tacrolimus.

American journal of ophthalmology case reports·2020

Same author

Topical Tacrolimus in Thygeson Superficial Punctate Keratitis.

Cornea·2019

Same author

Assessment of Ophthalmology Residency Programs in Saudi Arabia: A Trainee-Based Survey.

Journal of medical education and curricular development·2019

Same author

Initial misdiagnosis of Vogt-Koyanagi-Harada disease.

Saudi journal of ophthalmology : official journal of the Saudi Ophthalmological Society·2019

Search research articles

Related Experiment Video

Updated: Jun 2, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Tuberculosis.

Khalid F Tabbara¹

¹The Eye Center and The Eye Foundation for Research in Ophthalmology, Riyadh, Saudi Arabia. k.tabbara@nesma.net.sa

Current Opinion in Ophthalmology

|December 29, 2007

Summary

This summary is machine-generated.

Ocular tuberculosis, a global health concern, presents diverse eye symptoms and can mimic other conditions. Early diagnosis and treatment are crucial to prevent vision loss.

More Related Videos

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

Published on: June 30, 2019

Related Experiment Videos

Last Updated: Jun 2, 2026

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

A 3D Human Lung Tissue Model for Functional Studies on Mycobacterium tuberculosis Infection

Published on: October 5, 2015

Analysis of 18FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Analysis of ¹⁸FDG PET/CT Imaging as a Tool for Studying Mycobacterium tuberculosis Infection and Treatment in Non-human Primates

Published on: September 5, 2017

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

Use of the Invertebrate Galleria mellonella as an Infection Model to Study the Mycobacterium tuberculosis Complex

Published on: June 30, 2019

Area of Science:

Ophthalmology
Infectious Diseases
Public Health

Background:

Tuberculosis (TB) affects a significant portion of the global population, with increasing incidence linked to HIV.
Ocular TB can manifest in various forms, affecting both anterior and posterior segments of the eye.
Immunocompromised individuals, including those with HIV, are at higher risk for severe ocular TB, potentially leading to rapid vision loss.

Purpose of the Study:

To provide an updated overview of the clinical manifestations of ocular tuberculosis.
To review current diagnostic and management strategies for ocular tuberculosis.

Main Methods:

Review of clinical presentations of ocular tuberculosis.
Discussion of diagnostic techniques including microbiological isolation (Löwestein-Jensen, PCR), imaging (OCT, angiography, ultrasonography), and skin testing.
Analysis of treatment approaches for ocular tuberculosis.

Main Results:

Ocular TB presents with varied signs, including scleritis, anterior granulomatous uveitis, vitritis, and choroiditis.
The condition can mimic other ocular diseases, complicating diagnosis.
Diagnostic confirmation relies on isolating Mycobacterium tuberculosis, supported by clinical findings and various imaging modalities.

Conclusions:

Ocular tuberculosis can occur independently of pulmonary disease.
Prompt diagnosis and timely intervention are essential to mitigate ocular morbidity and prevent blindness.
Recognizing the diverse presentations of ocular TB is key for effective management.