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Updated: Jul 8, 2026

Preparation and Delivery of Protein Microcrystals in Lipidic Cubic Phase for Serial Femtosecond Crystallography
Published on: September 20, 2016
Duplexiphane: a polyaromatic receptor containing two adjoined Delta-shaped cavities for an efficient hopping of a
Susanna J Emond1, Paromita Debroy, Rajendra Rathore
1Department of Chemistry, Marquette University, P.O. Box 1881, Milwaukee, Wisconsin 53201, USA.
Abstract:
A simple synthesis of a polyaromatic receptor (i.e., duplexiphane) containing two adjoined Delta-shaped cavities is accomplished via an intramolecular (double) McMurry coupling, and its structure is established by X-ray crystallography. The binding of silver cation to duplexiphane showed that it binds only a single silver cation with significantly higher efficiency (>100 times) than a model compound containing only one pi-prismand-like cavity, and the single silver cation hops intramolecularly between the two adjoined cavities in duplexiphane.
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