Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Angle Closure Glaucoma: Treatment01:28

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...
Glaucoma: Overview01:25

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...
Focusing of Light in the Eye01:16

Focusing of Light in the Eye

Light rays enter the eye through the cornea, a transparent dome-shaped tissue that is the eye's outermost layer. The cornea bends or refracts, light rays traveling to the pupil. The shape of the cornea determines how much of the light is bent and whether the image will be focused correctly on the retina at the back of the eye. Once the light has passed through both refraction layers, it converges into a single focal point onto a small area. This is where photoreceptors start transforming...
Open Angle Glaucoma: Treatment01:27

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...
Fascicle Arrangement in Skeletal Muscles01:25

Fascicle Arrangement in Skeletal Muscles

Fascicles are bundles of muscle fibers in a skeletal muscle. Muscle fascicle arrangement is directly associated with the power and range of motion of various muscles. The configuration of these fascicles can vary, leading to different functional outcomes.
The four primary types of muscle based on fascicle arrangement are:
Depth Perception and Spatial Vision01:15

Depth Perception and Spatial Vision

Depth perception is the ability to perceive objects three-dimensionally. It relies on two types of cues: binocular and monocular. Binocular cues depend on the combination of images from both eyes and how the eyes work together. Since the eyes are in slightly different positions, each eye captures a slightly different image. This disparity between images, known as binocular disparity, helps the brain interpret depth. When the brain compares these images, it determines the distance to an object.

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Pattern Electroretinogram in Glaucoma Suspects with Signs of Conversion: Diagnosis, Assessment, and Monitoring Treatment - Case Report.

Case reports in ophthalmology·2026
Same author

Oocyte maturation triggers in high-responders: a report on 1,217 consecutive cycles.

Reproduction & fertility·2025
Same author

Foveal Avascular Zone Enlargement as a Risk Factor for Early Retinal Ganglion Cell Dysfunction in Glaucoma Suspects.

Diagnostics (Basel, Switzerland)·2025
Same author

Standalone Canaloplasty and Trabeculotomy Using the OMNI Surgical System in Patients With Open Angle Glaucoma: A Systematic Review and Meta-analysis.

Journal of glaucoma·2025
Same author

Novel Structure-Function Models for Estimating Retinal Ganglion Cell Count Using Pattern Electroretinography in Glaucoma Suspects.

Diagnostics (Basel, Switzerland)·2025
Same author

Retinal Vessel Diameter Reductions Are Associated with Retinal Ganglion Cell Dysfunction, Thinning of the Ganglion Cell and Inner Plexiform Layers, and Decreased Visual Field Global Indices in Glaucoma Suspects.

Diagnostics (Basel, Switzerland)·2025
Same journal

Comparative analyses of the differentiation and stemness status of corneal epithelial cell lines in varying culture conditions.

Experimental eye research·2026
Same journal

Corneal deformation mapping and FE-based strain analysis via digital image correlation: Biomechanical changes after CXL and laser refractive surgery.

Experimental eye research·2026
Same journal

Tanshinone IIA inhibits choroidal neovascularization and restores outer blood-retinal barrier function in Vldlr knockout mice.

Experimental eye research·2026
Same journal

Understanding the ocular accumulation of mefuparib and its N-dealkylation metabolite: Pharmacokinetics, melanin affinity, and cellular disposition.

Experimental eye research·2026
Same journal

Mitochondrial Dysfunction and Diabetic Retinopathy: Research Progress from Pathogenic Mechanisms to Therapeutic Targets.

Experimental eye research·2026
Same journal

Middle-wavelength green ambient light attenuates lens-induced myopia progression and is associated with suppression of the Wnt/β-catenin signaling pathway in guinea pigs.

Experimental eye research·2026
See all related articles

Related Experiment Video

Updated: Jul 8, 2026

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher
05:14

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

Accommodation-induced changes in iris curvature.

Syril Dorairaj1, Cristiano Oliveira, Amanda K Fose

  • 1Department of Ophthalmology, The New York Eye and Ear Infirmary, New York, NY, USA.

Experimental Eye Research
|January 1, 2008
PubMed
Summary
This summary is machine-generated.

Iris contour changes with accommodation, particularly in pigment dispersion syndrome (PDS) and narrow angle eyes. PDS eyes showed the most significant, rapid iris curvature shifts during accommodation.

More Related Videos

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Related Experiment Videos

Last Updated: Jul 8, 2026

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher
05:14

Simulating the Mechanics of Lens Accommodation via a Manual Lens Stretcher

Published on: February 23, 2018

Iris Fixation via External Pentagram Suturing
05:22

Iris Fixation via External Pentagram Suturing

Published on: May 5, 2022

Area of Science:

  • Ophthalmology
  • Biomedical Optics
  • Anatomical Imaging

Background:

  • Accommodation involves dynamic changes in ocular structures.
  • Iris contour alterations during accommodation are not fully understood, especially in specific ocular conditions.

Purpose of the Study:

  • To compare iris contour changes during accommodation in eyes with narrow angles, pigment dispersion syndrome (PDS), and healthy controls.
  • To investigate the time-dependent nature of iris curvature response to accommodation.

Main Methods:

  • Anterior segment ultrasound biomicroscopy was used to image iris contour.
  • Iris curvature was measured in unaccommodated and accommodated states (immediately and at 3 minutes).
  • Measurements were compared between control subjects, eyes with narrow angles, and eyes with PDS.

Main Results:

  • Control subjects showed a non-significant decrease then increase in iris curvature.
  • Eyes with PDS exhibited a significant increase in iris curvature after 3 minutes of accommodation.
  • Eyes with narrow angles showed a significant increase in iris curvature after 3 minutes of accommodation.
  • PDS eyes demonstrated the largest immediate drop and most rapid subsequent increase in iris curvature.

Conclusions:

  • Iris contour response to accommodation is time-dependent.
  • Significant differences in iris curvature dynamics exist between control, narrow angle, and PDS eyes.
  • Rapid iris curvature increase in PDS eyes may be linked to reverse pupillary block and elevated anterior chamber pressure.