[Non-invasive topical ECG diagnosis of Wolff-Parkinson-White syndrome]

The paper deals with the procedures and techniques of the non-invasive topical ECG diagnosis of the Wolff-Parkinson-White syndrome, which were based on the regression analysis. Based on the analysis of ECG data and the results of intraoperative cardiac mapping in 64 patients operated on for the Wolff-Parkinson-White syndrome, a linear regression model was developed, which precisely localizes the site of the Kent bundle from the measurements of delta-wave amplitude and polarity in 12 standard leads. The site of the Kent bundle was determined by 30 zones of the atrioventricular sulcus. The model represented a linear statistical dependence of the zone number of the atrioventricular sulcus on the delta-wave amplitude. Its parameters were evaluated from the data obtained in the training group of 47 patients and the accuracy of the diagnosis was assessed from the data obtained in 17 controls. The testing of the model showed that the Kent bundle may be localized at an accuracy (0.79 +/- 0.16), on an average, no greater than 1 zone. The estimation error was no more than 1 zone in 88% of the cases and 2 zones in 12%. The proposed model may be widely used in in- and outpatient care, as its application requires no cost-effective equipment and computer facilities.